求日本和俄罗斯关于如何制备1,3-二溴-5,5-二甲基海因的专利

求日本和俄罗斯关于如何制备1,3-二溴-5,5-二甲基海因的专利
求日本和俄罗斯关于如何制备1,3-二溴-5,5-二甲基海因的专利

求日本和俄罗斯关于如何制备1,3-二溴-5,5-二甲基海因的专利
日本和俄罗斯没有它的制备专利,你要求也不要太高.相关合成文献基本都在下面了.
Process for producing N-halogenated hydantoins.Elnagar,Hassan Y.; Peters,Bruce C.; Spielman,Edgar E.; Thomas,Dustin H.(USA).17 pp.,US 2006036099
Preparation of dibromohydantoin bactericidal algaecides.Jiang,Yanyi.(Longkou Keda Chemical Co.,Ltd.,Peop.Rep.China).Faming Zhuanli Shenqing Gongkai Shuomingshu (2005),6 pp.CN 1611493
Process for producing N-halogenated organic compounds.Elnagar,Hassan Y.; Peters,Bruce C.; Spielman,Edgar E.; Thomas,Dustin H.(USA).US 2005049420
Preparation of 2,4-dibromo-5,5-dimethylhydantoin aqueous solution disinfectant.Zhou,Li-xue; Zhu,Yun-qi.Xuzhou College of Industrial Technology,Xuzhou,Peop.Rep.China.Nanjing Gongye Daxue Xuebao,Ziran Kexueban (2004),26(6),36-40.
Method for preparing 1,3-dibromo-5,5-dimethylhydantoin granule for killing harmful bacteria in the cultivating water source.Huang,Zhongping.(Zhongshun Biotechnology Co.,Ltd.,Wuxi,Peop.Rep.China).Faming Zhuanli Shenqing Gongkai Shuomingshu (2003),6 pp.CODEN:CNXXEV CN 1410363
Methods for microbiological control in aqueous systems.Howarth,Jonathan N.; Nalepa,Christopher J.; Sanders,Michael J.(Albemarle Corporation,USA).US 6641828
Study on synthesis and the antimicrobial activity of N,N-dihalo-5,5-dimethylhydantoin.Zhang,Shengli; Xu,Zuxun; Huang,Jingxia; Chen,Zuxing.Sch.Chem.Material Sci.,Hubei Univ.,Wuhan,Peop.Rep.China.Hubei Daxue Xuebao,Ziran Kexueban (2002),24(1),63-65.
Process for producing n-halogenated organic compounds.Elnagar,Hassan Y.; Peters,Bruce C.; Spielman,Edgar E.,Jr.; Thomas,Dustin H.(Albemarle Corporation,USA).PCT Int.Appl.(2001),55 pp.WO 2001053270
1,3-Dibromo-5,5-dimethylhydantoin of enhanced properties.Elnagar,Hassan Y.; Howarth,Jonathan N.; Peters,Bruce C.; Spielman,Edgar E.,Jr.; Thomas,Dustin H.(Albemarle Corporation,USA).PCT Int.Appl.(2001),31 pp.WO
Treatment of wastewater discharged from production of hydantoin's derivates.Huang,Jinxia; Yu,Guang'ao; Li,Rulan.Department of Chemistry,Hubei University,Wuhan,Peop.Rep.China.Jingxi Huagong (1998),15(2),55-58.
Compositions and methods utilizing 1,3-bromochloro-5-methyl-5-propylhydantoin.Bhattacharya,Bhabatosh.(Great Lakes Chemical Corporation,USA).PCT Int.Appl.(1997),24 pp WO 9743264
New Aspects on the Preparation of 1,3-Dibromo-5,5-dimethylhydantoin.Markish,Itzhak; Arrad,Onn.CHEMADA,Doar Na Hanegev,Israel.Industrial & Engineering Chemistry Research (1995),34(6),2125-7.（这份应该是最接近工业生产,也应是最准确的）
Synthesis of 1,3-dibromo-5,5-dimethylhydantoin.Xu,Zhanghuang; Huang,Jinxia; Li,Yan; Fang,Guosu.Dep.Chem.,Hubei Univ.,Wuhan,Peop.Rep.China.Huaxue Shiji (1994),16(5),307-8,311.
Organic synthesis using sodium bromate.II.A facile synthesis of N-bromo imides and amides using sodium bromate and hydrobromic acid (or sodium bromide) in the presence of sulfuric acid.Fujisaki,Shizuo; Hamura,Satoshi; Eguchi,Hisao; Nishida,Akiko.Fac.Eng.,Yamaguchi Univ.,Tokiwadai,Japan.Bulletin of the Chemical Society of Japan (1993),66(8),2426-8.
Densified halogenated dimethylhydantoins.Cole,Leon M.(Great Lakes Chemical Corp.,USA).U.S.(1985),5 pp.US 4532330
1,3-Dihalo-5,5-dialkylhydantoins.Bury,Zofia; Kwit,Daniela; Jaworska,Romana.(Instytut Farmaceutyczny).Pol.(1966),2 pp.PL 51580
Abstract:
The title compds.prepd.by the known method are easily sepd.from reaction mixts.and in this way the yields of the compds.are much higher than those of the 5,5-dialkylhydantoins.The method described makes it possible to avoid acidification of the reaction mixt.and in this way to prevent HCN evolution.Thus,120 g.NH4HCO3 is dissolved at 50 in 118 ml.25% NH3,50 ml.H2O,35 g.KCN,and 37 ml.Me2CO are added,the mixt.is heated 2.5 hrs.under vigorous stirring at 55-60 and 3 hrs.at 90 and cooled to 15.NaOH (42 g.) in 1000 ml.H2O is added,57 ml.Br dropped in during 30 min.,and the mixt.stirred at 10-15 1.5 hrs.and kept overnight to crystallize at room temp.to give 100 g.yellow cryst.product m.196-8,contg.99% 1,3-dibromo-5,5-dimethylhydantoin.1,3-Dichloro-5,5-dimethylhydantoin,m.130-2,is obtained similarly.
引用的!

去专利局查就知道了