英语翻译Makaluvamine C is a pyrroloiminoquinone which has been isolated from marine sponges.This molecule has been synthesized in 13 steps from p-anisidine.The key steps in this synthesis include an intramolecular nucleophilic aromatic substituti
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英语翻译Makaluvamine C is a pyrroloiminoquinone which has been isolated from marine sponges.This molecule has been synthesized in 13 steps from p-anisidine.The key steps in this synthesis include an intramolecular nucleophilic aromatic substituti
英语翻译
Makaluvamine C is a pyrroloiminoquinone which has been isolated from marine sponges.This molecule has been synthesized in 13 steps from p-anisidine.The key steps in this synthesis include an intramolecular nucleophilic aromatic substitution mediated by potassium tert-butoxide,the selective reduction of a dinitro ester using catalytic hydrogenation,and the novel use of Fremy's salt to synthesize an iminoquinone from an amino phenol.The synthesis of makaluvamine C has been achieved from p-anisidine in 13.1% overall yield.
英语翻译Makaluvamine C is a pyrroloiminoquinone which has been isolated from marine sponges.This molecule has been synthesized in 13 steps from p-anisidine.The key steps in this synthesis include an intramolecular nucleophilic aromatic substituti
Makaluvamine C 是一种从海绵动物中提取的一种亚氨基吡咯醌.这种物质是从对茴香胺(p-anisidine.)开始经过13步合成而来,合成的关键不周包括:叔丁醇钾盐介导的芳香亲和取代、利用催化氢化进行的二硝基酯的选择性还原,还有利用Fremy盐从氨基苯酚合成亚氨基醌.该合成路径的收率为13.1%.