作业帮英语翻译The presence of the mitotic regulators Cdr1 and Cdr2 in the inter-phase nodes prompted us to examine whether Blt1 also regulatesmitotic entry.blt1D cells had an increased length at division,consist-ent with a delay inmitotic entry.This ph
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英语翻译The presence of the mitotic regulators Cdr1 and Cdr2 in the inter-phase nodes prompted us to examine whether Blt1 also regulatesmitotic entry.blt1D cells had an increased length at division,consist-ent with a delay inmitotic entry.This ph
英语翻译
The presence of the mitotic regulators Cdr1 and Cdr2 in the inter-
phase nodes prompted us to examine whether Blt1 also regulates
mitotic entry.blt1D cells had an increased length at division,consist-
ent with a delay inmitotic entry.This phenotype was synthetic with a
temperature-sensitive cdc25ts
mutation (Supplementary Table 1),
but not with cdr1D and cdr2Dmutants,which act through Wee1 (refs
15–17).These genetic data are consistent both with the localization
hierarchy described earlier and with a pathway in which Cdr2 func-tions upstream of Cdr1 and Blt1 to promote mitosis through the
negative regulation of Wee1 (Fig.2b).
英语翻译The presence of the mitotic regulators Cdr1 and Cdr2 in the inter-phase nodes prompted us to examine whether Blt1 also regulatesmitotic entry.blt1D cells had an increased length at division,consist-ent with a delay inmitotic entry.This ph
有丝分裂间期出现了调控因子Cdr1和Cdr2,这促使我们检查Blt1是否也调控细胞进入有丝分裂.blt1D突变体细胞在分裂时长度增加,进入有丝分裂时间延迟一致.这种表型可以通过温度敏感型突变体cdc25ts获得（补充材料表1）,但是不能由通过Wee1作用的cdc1D和cdc2D突变体获得（refs 15-17）.这些遗传学数据与先前描述的细胞调控因子的层次关系一致,也与一条Cdr2在Cdr1和Blt1上游负调控Wee1而促进有丝分裂的通路相一致（图2b）.