(x+4)^2(x-4)^2 - (2x-1)^2(2x+4)^2

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(x+4)^2(x-4)^2 - (2x-1)^2(2x+4)^2
(x+4)^2(x-4)^2 - (2x-1)^2(2x+4)^2

(x+4)^2(x-4)^2 - (2x-1)^2(2x+4)^2
(x+4)^2(x-4)^2 - (2x-1)^2(2x+4)^2
=[(x+4)(x-4)]^2-[(2x-1)(2x+4)]^2
=(x^2-16)^2-(4x^2+6x-4)^2
=x^4-32x^2-256-(16x^4+48x^3+4x^2-48x+16)
=-15x^4-48x^3-36x^2+48x-272

= [(x+4)(x-4)]^2 - [2(2x-1)(x+2)]^2
=[(x+4)(x-4)+2(2x-1)(x+2)]*[(x+4)(x-4)-2(2x-1)(x+2)]
=[x^2-16 + 4x^2-6x-2][x^2-16 - 4x^2+6x+2]
=[5x^2-6x-18][-3x^2+6x-14]

= [(x+4)(x-4)]^2 - [(2x-1)(2x+4)]^2
=[(x+4)(x-4)+(2x-1)(2x+4)]*[(x+4)(x-4)-(2x-1)(2x+4)]
=[x^2-16 + 4x^2+6x-4][x^2-16 - 4x^2-6x+4]
=[5x^2+6x-20][-3x^2-6x-12]