Nobody can avoid making mistakes in life—it is how to learn from hese mistakes____makes a bigdifference.which what whether that

Nobody can avoid making mistakes in life—it is how to learn from hese mistakes____makes a bigdifference.which what whether that
Nobody can avoid making mistakes in life—it is how to learn from hese mistakes____makes a big
difference.
which what whether that

Nobody can avoid making mistakes in life—it is how to learn from hese mistakes____makes a bigdifference.which what whether that
Nobody can avoid making mistakes in life—it is how to learn from these mistakes【that】makes a big difference.
这是强调句,去掉强调结构,it is that,句子结构依然完整,
【how to learn from these mistakes】主语【makes】谓语 【a big difference】宾语.
句子结构齐全,所以是强调句,选择that.
无疑后请采纳.
书山有路勤为径,学海无涯苦作舟.
-----------与君共勉-----------