英语翻译Analysis of HLAmatching was based on typing for HLA-A and -B antigensby serologic methods and for HLA-DR by serologic typing or DNAtechniques (restriction fragment length polymorphisms or sequencespecificoligonucleotide probes) as reporte

英语翻译Analysis of HLAmatching was based on typing for HLA-A and -B antigensby serologic methods and for HLA-DR by serologic typing or DNAtechniques (restriction fragment length polymorphisms or sequencespecificoligonucleotide probes) as reporte
英语翻译
Analysis of HLAmatching was based on typing for HLA-A and -B antigens
by serologic methods and for HLA-DR by serologic typing or DNA
techniques (restriction fragment length polymorphisms or sequencespecific
oligonucleotide probes) as reported by institutions performing the
transplantations.All recipients of VUD SCT were “fully matched” according
to the HLAtyping strategy performed at the time of donor identification
in each center,and definitions of HLA-matching were considered with
respect to reagents available when typing was performed.
Disease characteristics before SCT
Recipient/donor age.The median age of recipients at transplantation was
14 years (range,younger than 12 months to 17 years) and was not
significantly different for children undergoing SCT from sibling or unrelated
donors.Information about donor age was available for 156 (86%)
siblings and 81 (61%) VUDs,and the median age of the former was
significantly lower than for VUD recipients (13 vs 33 years; P \3 .001)
(Table 1).
Sex.Of the 314 children included in this study,168 (54%) were boys
and 146 (46%) were girls with a male-female ratio of 1.15:1.0,which is
similar to that observed in adults.Asimilar proportion of sibling (27%) and
VUD (23%) transplantations was performed for the combination male
recipient/female donor.

英语翻译Analysis of HLAmatching was based on typing for HLA-A and -B antigensby serologic methods and for HLA-DR by serologic typing or DNAtechniques (restriction fragment length polymorphisms or sequencespecificoligonucleotide probes) as reporte
实施干细胞移植的研究单位报道称：人类白血球组织抗原（HLA）分型以HLA-A与HLA-B抗体分型为基础,通过血清学方法进行.而HLA-DR分型则通过血清学分型或DNA技术（如限制性片段长度多态性,RFLP；或序列特异性寡核苷酸探针,SSOP）进行.按照各中心供体鉴定HLA分型策略,所有无关供体（志愿者）造血干细胞移植受体完全匹配.“and definitions of HLA-matching were considered with respect to reagents available when typing was performed.”这句需要好好磋磨.
实施造血干细胞移植前患者疾病状况
受体年龄与供体年龄.接受移植时受体患者年龄为12个月至17周岁不等,中位数为14周岁.与同胞供体或无关供体相比,造血干细胞移植受体年龄无显著性差异.156例同胞供体的年龄信息已知,占86%,81例无关受体年龄信息已知,占61%.前者年龄中位数为13周岁,明显低于后者（33周岁,P

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